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Role for LAMP-2 in endosomal cholesterol transport

The mechanisms of endosomal and lysosomal cholesterol traffic are still poorly understood. We showed previously that unesterified cholesterol accumulates in the late endosomes and lysosomes of fibroblasts deficient in both lysosome associated membrane protein-2 (LAMP-2) and LAMP-1, two abundant memb...

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Detalles Bibliográficos
Autores principales: Schneede, Alexander, Schmidt, Christine K, Hölttä-Vuori, Maarit, Heeren, Jörg, Willenborg, Marion, Blanz, Judith, Domanskyy, Mykola, Breiden, Bernadette, Brodesser, Susanne, Landgrebe, Jobst, Sandhoff, Konrad, Ikonen, Elina, Saftig, Paul, Eskelinen, Eeva-Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822795/
https://www.ncbi.nlm.nih.gov/pubmed/19929948
http://dx.doi.org/10.1111/j.1582-4934.2009.00973.x