The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling

Charcot-Marie-Tooth disease type 4B is caused by mutations in the genes encoding either the lipid phosphatase myotubularin-related protein-2 (MTMR2) or its regulatory binding partner MTMR13/SBF2. Mtmr2 dephosphorylates PI-3-P and PI-3,5-P2 to form phosphatidylinositol and PI-5-P, respectively, while...

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Detalles Bibliográficos
Autores principales: Berger, Philipp, Tersar, Kristian, Ballmer-Hofer, Kurt, Suter, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822797/
https://www.ncbi.nlm.nih.gov/pubmed/19912440
http://dx.doi.org/10.1111/j.1582-4934.2009.00967.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822797/
https://www.ncbi.nlm.nih.gov/pubmed/19912440
http://dx.doi.org/10.1111/j.1582-4934.2009.00967.x

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