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Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice

Anti-angiogenesis represents a promising therapeutic strategy for the treatment of various malignancies. Isthmin (ISM) is a gene highly expressed in the isthmus of the midbrain–hindbrain organizer in Xenopus with no known functions. It encodes a secreted 60 kD protein containing a thrombospondin typ...

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Detalles Bibliográficos
Autores principales: Xiang, Wei, Ke, Zhiyuan, Zhang, Yong, Ho-Yuet Cheng, Grace, Irwan, Ishak Darryl, Sulochana, K N, Potturi, Padma, Wang, Zhengyuan, Yang, He, Wang, Jingyu, Zhuo, Lang, Kini, R Manjunatha, Ge, Ruowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822802/
https://www.ncbi.nlm.nih.gov/pubmed/19874420
http://dx.doi.org/10.1111/j.1582-4934.2009.00961.x