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Mesenchymal stem cells modified to express lentivirus TNF-α Tumstatin(45–132) inhibit the growth of prostate cancer

Mesenchymal stem cells (MSCs) are a potential novel delivery system for cell-based gene therapies. Although tumour necrosis factor (TNF)-α has been shown to have antitumour activity, its use in therapy is limited by its systemic toxicity. For the present study, we designed lentivirus-mediated signal...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Xu, Wenrong, Qian, Hui, Zhu, Wei, Zhang, Ruiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822807/
https://www.ncbi.nlm.nih.gov/pubmed/19799647
http://dx.doi.org/10.1111/j.1582-4934.2009.00920.x