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Mesenchymal stem cells modified to express lentivirus TNF-α Tumstatin(45–132) inhibit the growth of prostate cancer
Mesenchymal stem cells (MSCs) are a potential novel delivery system for cell-based gene therapies. Although tumour necrosis factor (TNF)-α has been shown to have antitumour activity, its use in therapy is limited by its systemic toxicity. For the present study, we designed lentivirus-mediated signal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822807/ https://www.ncbi.nlm.nih.gov/pubmed/19799647 http://dx.doi.org/10.1111/j.1582-4934.2009.00920.x |