Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase γ (POLG) gene: a combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study

Combined morphological, immunocytochemical, biochemical and molecular genetic studies were performed on skeletal muscle, heart muscle and liver tissue of a 16-months boy with fatal liver failure. The pathological characterization of the tissues revealed a severe depletion of mtDNA (mitochondrial DNA...

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Detalles Bibliográficos
Autores principales: Müller-Höcker, J, Horvath, R, Schäfer, S, Hessel, H, Müller-Felber, W, Kühr, J, Copeland, W C, Seibel, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822808/
https://www.ncbi.nlm.nih.gov/pubmed/19538466
http://dx.doi.org/10.1111/j.1582-4934.2009.00819.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822808/
https://www.ncbi.nlm.nih.gov/pubmed/19538466
http://dx.doi.org/10.1111/j.1582-4934.2009.00819.x

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