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SULT1A1 gene deletion in BRCA2-associated male breast cancer: a link between genes and environmental exposures?

SULT1A1, a member of sulfotransferase superfamily, is a drug and hormone metabolizing enzyme involved in the metabolism of a variety of potential mammary carcinogens of endogenous and exogenous origin. Interestingly, the metabolic activity of SULT1A1 can be affected by variations in gene copy number...

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Detalles Bibliográficos
Autores principales: Palli, Domenico, Rizzolo, Piera, Zanna, Ines, Silvestri, Valentina, Saieva, Calogero, Falchetti, Mario, Navazio, Anna Sara, Graziano, Veronica, Masala, Giovanna, Bianchi, Simonetta, Russo, Antonio, Tommasi, Stefania, Ottini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822812/
https://www.ncbi.nlm.nih.gov/pubmed/23711090
http://dx.doi.org/10.1111/jcmm.12043