Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells

Triple-negative breast cancers (TNBCs) are known to be intrinsically resistant to inhibitors for epidermal growth factor receptor (EGFR). Until now, clinical trials for TNBCs using EGFR inhibitors (EGFRis) as single agents have yielded disappointing results. Here, we report that combinatorial treatm...

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Detalles Bibliográficos
Autores principales: Yi, Yong Weon, Hong, Wooyoung, Kang, Hyo Jin, Kim, Hee Jeong, Zhao, Wenjing, Wang, Antai, Seong, Yeon-Sun, Bae, Insoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822817/
https://www.ncbi.nlm.nih.gov/pubmed/23601074
http://dx.doi.org/10.1111/jcmm.12046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822817/
https://www.ncbi.nlm.nih.gov/pubmed/23601074
http://dx.doi.org/10.1111/jcmm.12046

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