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FTY720 attenuates accumulation of EMAP-II(+) and MHC-II(+) monocytes in early lesions of rat traumatic brain injury

FTY720 (Fingolimod) is a novel type of immunosuppressive agent inhibiting lymphocyte egress from secondary lymphoid tissues thereby causing peripheral lymphopenia. FTY720 can inhibit macrophage infiltration into inflammatory lesions under pathological conditions. FTY720 has been clinically evaluated...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiyuan, Zhang, Zhiren, Fauser, Uwe, Artelt, Matthias, Burnet, Michael, Schluesener, Hermann J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822829/
https://www.ncbi.nlm.nih.gov/pubmed/17488479
http://dx.doi.org/10.1111/j.1582-4934.2007.00019.x