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FTY720 attenuates accumulation of EMAP-II(+) and MHC-II(+) monocytes in early lesions of rat traumatic brain injury
FTY720 (Fingolimod) is a novel type of immunosuppressive agent inhibiting lymphocyte egress from secondary lymphoid tissues thereby causing peripheral lymphopenia. FTY720 can inhibit macrophage infiltration into inflammatory lesions under pathological conditions. FTY720 has been clinically evaluated...
Autores principales: | Zhang, Zhiyuan, Zhang, Zhiren, Fauser, Uwe, Artelt, Matthias, Burnet, Michael, Schluesener, Hermann J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822829/ https://www.ncbi.nlm.nih.gov/pubmed/17488479 http://dx.doi.org/10.1111/j.1582-4934.2007.00019.x |
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