bcl-2-specific siRNAs restore Gemcitabine sensitivity in human pancreatic cancer cells

Gemcitabine has been shown to ameliorate disease related symptoms and to prolong overall survival in pancreatic cancer.Yet, resistance to Gemcitabine is commonly observed in this tumour entity and has been linked to increased expression of anti-apoptotic bcl-2. We therefore investigated if and to wh...

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Detalles Bibliográficos
Autores principales: Okamoto, Kinya, Ocker, Matthias, Neureiter, Daniel, Dietze, Otto, Zopf, Steffen, Hahn, Eckhart G, Herold, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822833/
https://www.ncbi.nlm.nih.gov/pubmed/17378914
http://dx.doi.org/10.1111/j.1582-4934.2007.00013.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822833/
https://www.ncbi.nlm.nih.gov/pubmed/17378914
http://dx.doi.org/10.1111/j.1582-4934.2007.00013.x

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