Cargando…

Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice

Progranulin haploinsufficiency is associated with frontotemporal dementia in humans. Deficiency of progranulin led to exaggerated inflammation and premature aging in mice. The role of progranulin in adaptations to nerve injury and neuropathic pain are still unknown. Here we found that progranulin is...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Hee-Young, Albuquerque, Boris, Häussler, Annett, Myrczek, Thekla, Ding, Aihao, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822842/
https://www.ncbi.nlm.nih.gov/pubmed/21645236
http://dx.doi.org/10.1111/j.1582-4934.2011.01350.x