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Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice
Progranulin haploinsufficiency is associated with frontotemporal dementia in humans. Deficiency of progranulin led to exaggerated inflammation and premature aging in mice. The role of progranulin in adaptations to nerve injury and neuropathic pain are still unknown. Here we found that progranulin is...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822842/ https://www.ncbi.nlm.nih.gov/pubmed/21645236 http://dx.doi.org/10.1111/j.1582-4934.2011.01350.x |