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Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

Connective tissue growth factor (CTGF/CCN-2) is mainly involved in the induction of extracellular matrix (ECM) proteins. The levels of CTGF correlate with the degree and severity of fibrosis in many tissues, including dystrophic skeletal muscle. The CTGF overexpression in tibialis anterior skeletal...

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Detalles Bibliográficos
Autores principales: Cabello-Verrugio, Claudio, Morales, María Gabriela, Cabrera, Daniel, Vio, Carlos P, Brandan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822846/
https://www.ncbi.nlm.nih.gov/pubmed/21645240
http://dx.doi.org/10.1111/j.1582-4934.2011.01354.x