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K(ATP) channel agonists preserve connexin43 protein in infarcted rats by a protein kinase C-dependent pathway

Downward remodelling of gap junctional proteins between myocytes may trigger ventricular arrhythmia after myocardial infarction. We have demonstrated that ATP-sensitive potassium (K(ATP)) channel agonists attenuated post-infarction arrhythmias. However, the involved mechanisms remain unclear. The pu...

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Detalles Bibliográficos
Autores principales: Lee, Tsung-Ming, Lin, Chih-Chan, Lien, Hsiao-Yin, Chen, Chien-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822848/
https://www.ncbi.nlm.nih.gov/pubmed/21692984
http://dx.doi.org/10.1111/j.1582-4934.2011.01366.x