Cargando…

Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1–actin complex in breast cancer cells

Profilin1 (Pfn1) functions as a tumour suppressor against malignant phenotypes of cancer cells. A minimum level of Pfn1 is critical for the differentiation of human epithelial cells, and its lower expression correlates with the tumourigenesis of breast cancer cells and tissues. However, the molecula...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Wantong, Yu, Xianjun, Fang, Zhengyu, Yin, Peng, Zhao, Chao, Li, Na, Wang, Liying, Li, Zengxia, Zha, Xiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822851/
https://www.ncbi.nlm.nih.gov/pubmed/21692986
http://dx.doi.org/10.1111/j.1582-4934.2011.01369.x