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Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1–actin complex in breast cancer cells

Profilin1 (Pfn1) functions as a tumour suppressor against malignant phenotypes of cancer cells. A minimum level of Pfn1 is critical for the differentiation of human epithelial cells, and its lower expression correlates with the tumourigenesis of breast cancer cells and tissues. However, the molecula...

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Detalles Bibliográficos
Autores principales: Yao, Wantong, Yu, Xianjun, Fang, Zhengyu, Yin, Peng, Zhao, Chao, Li, Na, Wang, Liying, Li, Zengxia, Zha, Xiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822851/
https://www.ncbi.nlm.nih.gov/pubmed/21692986
http://dx.doi.org/10.1111/j.1582-4934.2011.01369.x

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