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Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1–actin complex in breast cancer cells
Profilin1 (Pfn1) functions as a tumour suppressor against malignant phenotypes of cancer cells. A minimum level of Pfn1 is critical for the differentiation of human epithelial cells, and its lower expression correlates with the tumourigenesis of breast cancer cells and tissues. However, the molecula...
Autores principales: | Yao, Wantong, Yu, Xianjun, Fang, Zhengyu, Yin, Peng, Zhao, Chao, Li, Na, Wang, Liying, Li, Zengxia, Zha, Xiliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822851/ https://www.ncbi.nlm.nih.gov/pubmed/21692986 http://dx.doi.org/10.1111/j.1582-4934.2011.01369.x |
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