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Activators and inhibitors of the plasminogen system in Alzheimer’s disease
Accumulation and deposition of Aβ is one of the main neuropathological hallmarks of Alzheimer’s disease (AD) and impaired Aβ degradation may be one mechanism of accumulation. Plasmin is the key protease of the plasminogen system and can cleave Aβ. Plasmin is activated from plasminogen by tissue plas...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822855/ https://www.ncbi.nlm.nih.gov/pubmed/21790972 http://dx.doi.org/10.1111/j.1582-4934.2011.01394.x |