A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

Genes can maintain spatiotemporal expression patterns by long-range interactions between cis-acting elements. The cystic fibrosis transmembrane conductance regulator gene (CFTR) is expressed primarily in epithelial cells. An element located within a DNase I-hyper-sensitive site (DHS) 10 kb into the...

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Detalles Bibliográficos
Autores principales: Ott, Christopher J, Suszko, Magdalena, Blackledge, Neil P, Wright, Jane E, Crawford, Gregory E, Harris, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822875/
https://www.ncbi.nlm.nih.gov/pubmed/19449463
http://dx.doi.org/10.1111/j.1582-4934.2008.00621.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822875/
https://www.ncbi.nlm.nih.gov/pubmed/19449463
http://dx.doi.org/10.1111/j.1582-4934.2008.00621.x

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