Conditional knockdown of hMRS2 results in loss of mitochondrial Mg (+) uptake and cell death

The human gene MRS2L encodes a mitochondrial protein distantly related to CorA Mg(2+) transport proteins. Constitutive shRNA-mediated knockdown of hMRS2 in human HEK-293 cell line was found here to cause death. To further study its role in Mg(2+) transport, we have established stable cell lines with...

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Detalles Bibliográficos
Autores principales: Piskacek, Martin, Zotova, Ludmila, Zsurka, Gábor, Schweyen, Rudolf J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822876/
https://www.ncbi.nlm.nih.gov/pubmed/18384665
http://dx.doi.org/10.1111/j.1582-4934.2008.00328.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822876/
https://www.ncbi.nlm.nih.gov/pubmed/18384665
http://dx.doi.org/10.1111/j.1582-4934.2008.00328.x

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