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Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation

Fibroblast apoptosis plays a crucial role in normal and pathological scar formation and therefore we studied whether the putative apoptosis-inducing factor curcumin affects fibroblast apoptosis and may function as a novel therapeutic. We show that 25-μM curcumin causes fibroblast apoptosis and that...

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Detalles Bibliográficos
Autores principales: Scharstuhl, A, Mutsaers, HAM, Pennings, SWC, Szarek, WA, Russel, FGM, Wagener, FADTG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822878/
https://www.ncbi.nlm.nih.gov/pubmed/18410527
http://dx.doi.org/10.1111/j.1582-4934.2008.00339.x