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AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma β-cells

The effect of leucine on glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells is quite controversial, and mechanism involved in the effect has not been elucidated yet. Consequently, we aimed to investigate effect of leucine on GSIS and its mechanism focusing on contribution of AMP-activ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiujuan, Sun, Nannan, Wang, Laicheng, Guo, Hua, Guan, Qingbo, Cui, Bin, Tian, Limin, Gao, Ling, Zhao, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822882/
https://www.ncbi.nlm.nih.gov/pubmed/19438972
http://dx.doi.org/10.1111/j.1582-4934.2009.00656.x