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Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis

Oxidative stress, caused by reactive oxygen species (ROS), is a major contributor to inflammatory bowel disease (IBD)-associated neoplasia. We mimicked ROS exposure of the epithelium in IBD using non-tumour human colonic epithelial cells (HCEC) and hydrogen peroxide (H(2)O(2)). A population of HCEC...

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Detalles Bibliográficos
Autores principales: Poehlmann, Angela, Reissig, Kathrin, Just, Andrea, Walluscheck, Diana, Hartig, Roland, Schinlauer, Antje, Lessel, Wiebke, Guenther, Thomas, Silver, Andrew, Steinberg, Pablo, Roessner, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822895/
https://www.ncbi.nlm.nih.gov/pubmed/23742011
http://dx.doi.org/10.1111/jcmm.12079