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IL-10 production in non–small cell lung carcinoma patients is regulated by ERK, P38 and COX-2
Immune dysfunction is hallmark of patients with non–small cell lung carcinoma (NSCLC). The molecular mechanism involved in COX-2– and PGE2-mediated production of immunosuppressive cytokine IL-10 is not well-understood. Our study addresses the involvement of T cell downstream signalling intermediates...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822929/ https://www.ncbi.nlm.nih.gov/pubmed/21507199 http://dx.doi.org/10.1111/j.1582-4934.2011.01329.x |