Cargando…

IL-10 production in non–small cell lung carcinoma patients is regulated by ERK, P38 and COX-2

Immune dysfunction is hallmark of patients with non–small cell lung carcinoma (NSCLC). The molecular mechanism involved in COX-2– and PGE2-mediated production of immunosuppressive cytokine IL-10 is not well-understood. Our study addresses the involvement of T cell downstream signalling intermediates...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Swati, Vetale, Shamal, Teli, Pradeep, Mistry, Rajesh, Chiplunkar, Shubhada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822929/
https://www.ncbi.nlm.nih.gov/pubmed/21507199
http://dx.doi.org/10.1111/j.1582-4934.2011.01329.x