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IL-10 production in non–small cell lung carcinoma patients is regulated by ERK, P38 and COX-2

Immune dysfunction is hallmark of patients with non–small cell lung carcinoma (NSCLC). The molecular mechanism involved in COX-2– and PGE2-mediated production of immunosuppressive cytokine IL-10 is not well-understood. Our study addresses the involvement of T cell downstream signalling intermediates...

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Detalles Bibliográficos
Autores principales:	Patel, Swati, Vetale, Shamal, Teli, Pradeep, Mistry, Rajesh, Chiplunkar, Shubhada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822929/ https://www.ncbi.nlm.nih.gov/pubmed/21507199 http://dx.doi.org/10.1111/j.1582-4934.2011.01329.x

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