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E2F-1- and E2Ftr-mediated apoptosis: the role of DREAM and HRK

E2F-1-deleted mutant, ‘truncated E2F’ (E2Ftr, E2F-1[1–375]), lacking the carboxy-terminal transactivation domain, was shown to be more potent at inducing cancer cell apoptosis than wild-type E2F-1 (wtE2F-1; full-length E2F-1). Mechanisms by which wtE2F-1 and E2Ftr induce apoptosis, however, are not...

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Detalles Bibliográficos
Autores principales: Hao, Hongying, Chen, Canming, Rao, Xiao-Mei, Gomez-Gutierrez, Jorge G, Zhou, H Sam, McMasters, Kelly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822935/
https://www.ncbi.nlm.nih.gov/pubmed/21564512
http://dx.doi.org/10.1111/j.1582-4934.2011.01338.x