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P60TRP interferes with the GPCR/secretase pathway to mediate neuronal survival and synaptogenesis
In the present study, we show that overexpression of the G-protein-coupled receptor (GPCR)-associated sorting protein p60TRP (transcription regulator protein) in neural stem cells (NSCs) and in a transgenic mouse model modulates the phosphorylation and proteolytic processing of amyloid precursor pro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822957/ https://www.ncbi.nlm.nih.gov/pubmed/21199326 http://dx.doi.org/10.1111/j.1582-4934.2010.01248.x |