Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand

Targeting and down-regulation of ErbB2, a member of EGF receptor family, is regarded as one of the key aspect for cancer treatment because it is often overexpressed in breast and ovarian cancer cells. Although natural ligands for ErbB2 have not been found, unlike other ErbB receptors, EC-1, a 20-ami...

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Detalles Bibliográficos
Autores principales: Vaidyanath, Arun, Hashizume, Toshihiro, Nagaoka, Tadahiro, Takeyasu, Nao, Satoh, Hitomi, Chen, Ling, Wang, Jiyou, Kasai, Tomonari, Kudoh, Takayuki, Satoh, Ayano, Fu, Li, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822962/
https://www.ncbi.nlm.nih.gov/pubmed/21323863
http://dx.doi.org/10.1111/j.1582-4934.2011.01277.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822962/
https://www.ncbi.nlm.nih.gov/pubmed/21323863
http://dx.doi.org/10.1111/j.1582-4934.2011.01277.x

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