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Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand
Targeting and down-regulation of ErbB2, a member of EGF receptor family, is regarded as one of the key aspect for cancer treatment because it is often overexpressed in breast and ovarian cancer cells. Although natural ligands for ErbB2 have not been found, unlike other ErbB receptors, EC-1, a 20-ami...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822962/ https://www.ncbi.nlm.nih.gov/pubmed/21323863 http://dx.doi.org/10.1111/j.1582-4934.2011.01277.x |