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Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2

The HMG-CoA reductase inhibitors (statins) have been shown to exert several protective effects on the vasculature that are unrelated to changes in the cholesterol profile, and to induce angiogenesis. The proangiogenic effect exerted by statins has been attributed to the activation of the PI3K/Akt pa...

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Detalles Bibliográficos
Autores principales: Shiota, Masayuki, Hikita, Yuko, Kawamoto, Yukiko, Kusakabe, Hiromi, Tanaka, Masako, Izumi, Yasukatsu, Nakao, Takafumi, Miura, Katsuyuki, Funae, Yoshihiko, Iwao, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822970/
https://www.ncbi.nlm.nih.gov/pubmed/22117815
http://dx.doi.org/10.1111/j.1582-4934.2011.01494.x