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Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL
Zeta-associated protein of 70 kD (ZAP70) is a recognized adverse prognostic marker in chronic lymphocytic leukaemia (CLL) associated with enhanced B-cell receptor signalling, significantly more aggressive disease course and poor overall survival. Zeta-associated protein of 70 kD is ordinarily expres...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822977/ https://www.ncbi.nlm.nih.gov/pubmed/22151263 http://dx.doi.org/10.1111/j.1582-4934.2011.01503.x |