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Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL

Zeta-associated protein of 70 kD (ZAP70) is a recognized adverse prognostic marker in chronic lymphocytic leukaemia (CLL) associated with enhanced B-cell receptor signalling, significantly more aggressive disease course and poor overall survival. Zeta-associated protein of 70 kD is ordinarily expres...

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Detalles Bibliográficos
Autores principales: Amin, Shilu, Walsh, Meagan, Wilson, Caroline, Parker, Anton E, Oscier, David, Willmore, Elaine, Mann, Derek, Mann, Jelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822977/
https://www.ncbi.nlm.nih.gov/pubmed/22151263
http://dx.doi.org/10.1111/j.1582-4934.2011.01503.x

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