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Cystamine attenuates lupus-associated apoptosis of ventricular tissue by suppressing both intrinsic and extrinsic pathways

Cystamine, a disulphide metabolite, has been demonstrated to ameliorate various lupus-associated tissue damages by animal models. However, effects of cystamine on apoptosis of cardiac tissue, a main cardiac damage attributing to lupus, are less obvious. Therefore, we aimed to investigate whether or...

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Detalles Bibliográficos
Autores principales: Tzang, Bor-Show, Hsu, Tsai-Ching, Kuo, Cheng-Yi, Chen, Tzy-Yen, Chiang, Szu-Yi, Li, Sin-Lun, Kao, Shao-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822980/
https://www.ncbi.nlm.nih.gov/pubmed/22212591
http://dx.doi.org/10.1111/j.1582-4934.2011.01511.x