Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity

The Neurofibromatosis 2 (NF2) gene product merlin is a tumour suppressor, which in addition to inhibiting cell proliferation regulates cell morphology. The morphogenic properties of merlin may play a role in tumour suppression, as patient-derived tumour cells demonstrate cytoskeletal abnormalities....

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Detalles Bibliográficos
Autores principales: Laulajainen, Minja, Melikova, Maria, Muranen, Taru, Carpén, Olli, Grönholm, Mikaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822986/
https://www.ncbi.nlm.nih.gov/pubmed/22325036
http://dx.doi.org/10.1111/j.1582-4934.2012.01525.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822986/
https://www.ncbi.nlm.nih.gov/pubmed/22325036
http://dx.doi.org/10.1111/j.1582-4934.2012.01525.x

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