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Kynurenines, neurodegeneration and Alzheimer’s disease

Alzheimer’s disease (AD) is one of the major causes of dementia. The pathogenesis of the disease is not entirely understood, but the amyloid β peptide (Aβ) and the formation of senile plaques seem to play pivotal roles. Oligomerization of the Aβ is thought to trigger a cascade of events, including o...

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Detalles Bibliográficos
Autores principales: Kincses, Zsigmond Tamas, Toldi, József, Vécsei, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822995/
https://www.ncbi.nlm.nih.gov/pubmed/20629991
http://dx.doi.org/10.1111/j.1582-4934.2010.01123.x