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Fibroblast growth factor 2-antagonist activity of a long-pentraxin 3-derived anti-angiogenic pentapeptide

Fibroblast growth factor-2 (FGF2) plays a major role in angiogenesis. The pattern recognition receptor long-pentraxin 3 (PTX3) inhibits the angiogenic activity of FGF2. To identify novel FGF2-antagonistic peptide(s), four acetylated (Ac) synthetic peptides overlapping the FGF2-binding region PTX3-(9...

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Detalles Bibliográficos
Autores principales: Leali, Daria, Bianchi, Roberta, Bugatti, Antonella, Nicoli, Stefania, Mitola, Stefania, Ragona, Laura, Tomaselli, Simona, Gallo, Grazia, Catello, Sergio, Rivieccio, Vincenzo, Zetta, Lucia, Presta, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823002/
https://www.ncbi.nlm.nih.gov/pubmed/19627396
http://dx.doi.org/10.1111/j.1582-4934.2009.00855.x