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High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue

The KRAS mutation status predicts the outcome of treatment with epidermal growth factor receptor targeted agents, and therefore the testing for KRAS mutations has become an important diagnostic procedure. To optimize the quality of this test, we compared the results of the two most commonly used KRA...

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Detalles Bibliográficos
Autores principales: Tol, Jolien, Dijkstra, Jeroen R, Vink-Börger, Marianne E, Nagtegaal, Iris D, Punt, Cornelis JA, Van Krieken, Johan HJM, Ligtenberg, Marjolijn JL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823003/
https://www.ncbi.nlm.nih.gov/pubmed/19453520
http://dx.doi.org/10.1111/j.1582-4934.2009.00788.x