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The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells

The role of hydrogen sulfide (H(2)S) in inflammation remains unclear with both pro- and anti-inflammatory actions of this gas described. We have now assessed the effect of GYY4137 (a slow-releasing H(2)S donor) on lipopolysaccharide (LPS)-evoked release of inflammatory mediators from human synoviocy...

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Detalles Bibliográficos
Autores principales: Li, Ling, Fox, Bridget, Keeble, Julie, Salto-Tellez, Manuel, Winyard, Paul G, Wood, Mark E, Moore, Philip K, Whiteman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823018/
https://www.ncbi.nlm.nih.gov/pubmed/23356870
http://dx.doi.org/10.1111/jcmm.12016