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Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling

An important limitation in the clinical use of opiates is progressive loss of analgesic efficacy over time. Development of analgesic tolerance is tightly linked to receptor desensitization. In the case of delta opioid receptors (DOR), desensitization is especially swift because receptors are rapidly...

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Detalles Bibliográficos
Autores principales: Archer-Lahlou, Elodie, Audet, Nicolas, Amraei, Mohammad Gholi, Huard, Karine, Paquin-Gobeil, Mélanie, Pineyro, Graciela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823043/
https://www.ncbi.nlm.nih.gov/pubmed/18363847
http://dx.doi.org/10.1111/j.1582-4934.2008.00308.x