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Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling
An important limitation in the clinical use of opiates is progressive loss of analgesic efficacy over time. Development of analgesic tolerance is tightly linked to receptor desensitization. In the case of delta opioid receptors (DOR), desensitization is especially swift because receptors are rapidly...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823043/ https://www.ncbi.nlm.nih.gov/pubmed/18363847 http://dx.doi.org/10.1111/j.1582-4934.2008.00308.x |