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Molecular function prediction for a family exhibiting evolutionary tendencies toward substrate specificity swapping: Recurrence of tyrosine aminotransferase activity in the Iα subfamily

The subfamily Iα aminotransferases are typically categorized as having narrow specificity toward carboxylic amino acids (AATases), or broad specificity that includes aromatic amino acid substrates (TATases). Because of their general role in central metabolism and, more specifically, their associatio...

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Detalles Bibliográficos
Autores principales: Muratore, Kathryn E, Engelhardt, Barbara E, Srouji, John R, Jordan, Michael I, Brenner, Steven E, Kirsch, Jack F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823064/
https://www.ncbi.nlm.nih.gov/pubmed/23671031
http://dx.doi.org/10.1002/prot.24318