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Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer

MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression. Single nucleotide polymorphisms (SNPs) may occur in miRNA biogenesis pathway genes, primary miRNA, pre-miRNA or a mature miRNA sequence. Such polymorphisms may be functional with respect to biogenesis and actions of mature...

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Detalles Bibliográficos
Autores principales: Slaby, Ondrej, Bienertova-Vasku, Julie, Svoboda, Marek, Vyzula, Rostislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823089/
https://www.ncbi.nlm.nih.gov/pubmed/21692980
http://dx.doi.org/10.1111/j.1582-4934.2011.01359.x