Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules

The syntaxin 11 (STX11) gene is mutated in a proportion of patients with familial haemophagocytic lymphohistiocytosis (FHL) and exocytosis of cytotoxic granules is impaired in STX11-deficient NK cells. However, the subcellular localization, regulation of expression and molecular function of STX11 in...

Descripción completa

Detalles Bibliográficos
Autores principales: Dabrazhynetskaya, Alena, Ma, Jinxia, Guerreiro-Cacais, Andre Ortlieb, Arany, Zita, Rudd, Eva, Henter, Jan-Inge, Karre, Klas, Levitskaya, Jelena, Levitsky, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823099/
https://www.ncbi.nlm.nih.gov/pubmed/21342435
http://dx.doi.org/10.1111/j.1582-4934.2011.01280.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823099/
https://www.ncbi.nlm.nih.gov/pubmed/21342435
http://dx.doi.org/10.1111/j.1582-4934.2011.01280.x

Ejemplares similares