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Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules

The syntaxin 11 (STX11) gene is mutated in a proportion of patients with familial haemophagocytic lymphohistiocytosis (FHL) and exocytosis of cytotoxic granules is impaired in STX11-deficient NK cells. However, the subcellular localization, regulation of expression and molecular function of STX11 in...

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Detalles Bibliográficos
Autores principales:	Dabrazhynetskaya, Alena, Ma, Jinxia, Guerreiro-Cacais, Andre Ortlieb, Arany, Zita, Rudd, Eva, Henter, Jan-Inge, Karre, Klas, Levitskaya, Jelena, Levitsky, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823099/ https://www.ncbi.nlm.nih.gov/pubmed/21342435 http://dx.doi.org/10.1111/j.1582-4934.2011.01280.x

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