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Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

Maintenance of cellular pH homeostasis is fundamental to life. A number of key intracellular pH (pHi) regulating systems including the Na(+)/H(+) exchangers, the proton pump, the monocarboxylate transporters, the HCO(3)(−) transporters and exchangers and the membrane-associated and cytosolic carboni...

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Detalles Bibliográficos
Autores principales: Chiche, Johanna, Brahimi-Horn, M Christiane, Pouysségur, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823111/
https://www.ncbi.nlm.nih.gov/pubmed/20015196
http://dx.doi.org/10.1111/j.1582-4934.2009.00994.x