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Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
Maintenance of cellular pH homeostasis is fundamental to life. A number of key intracellular pH (pHi) regulating systems including the Na(+)/H(+) exchangers, the proton pump, the monocarboxylate transporters, the HCO(3)(−) transporters and exchangers and the membrane-associated and cytosolic carboni...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823111/ https://www.ncbi.nlm.nih.gov/pubmed/20015196 http://dx.doi.org/10.1111/j.1582-4934.2009.00994.x |