Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

Chromosomal instability (CIN), defined by an elevated frequency of the occurrence of novel chromosomal aberrations, is strongly implicated in the generation of aneuploidy, one of the hallmarks of human cancers. As for aneuploidy itself, the role of CIN in the evolution and progression of malignancy...

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Detalles Bibliográficos
Autores principales: Heilig, Christoph E, Löffler, Harald, Mahlknecht, Ulrich, Janssen, Johannes WG, Ho, Anthony D, Jauch, Anna, Krämer, Alwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823121/
https://www.ncbi.nlm.nih.gov/pubmed/19754665
http://dx.doi.org/10.1111/j.1582-4934.2009.00905.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823121/
https://www.ncbi.nlm.nih.gov/pubmed/19754665
http://dx.doi.org/10.1111/j.1582-4934.2009.00905.x

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