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The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells

Although natural killer (NK) cells are often described as first line defence against infected or malignant cells which act without the need of prior activation, it is known now that the NK cell activity is tightly regulated by other cells and soluble factors. We show here that the stress-inducible h...

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Detalles Bibliográficos
Autores principales: Elsner, Leslie, Flügge, Perris F, Lozano, Jingky, Muppala, Vijayakumar, Eiz-Vesper, Britta, Demiroglu, Sara Y, Malzahn, Dörthe, Herrmann, Thomas, Brunner, Edgar, Bickeböller, Heike, Multhoff, Gabriele, Walter, Lutz, Dressel, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823130/
https://www.ncbi.nlm.nih.gov/pubmed/20569278
http://dx.doi.org/10.1111/j.1582-4934.2008.00677.x