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Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells

The anticancer drug doxorubicin induces the synthesis of nitric oxide, a small molecule that enhances the drug cytotoxicity and reduces the drug efflux through the membrane pump P-glycoprotein (Pgp). Doxorubicin also induces the translocation on the plasma membrane of the protein calreticulin (CRT),...

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Detalles Bibliográficos
Autores principales: Kopecka, Joanna, Campia, Ivana, Brusa, Davide, Doublier, Sophie, Matera, Lina, Ghigo, Dario, Bosia, Amalia, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823194/
https://www.ncbi.nlm.nih.gov/pubmed/20716130
http://dx.doi.org/10.1111/j.1582-4934.2010.01137.x