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Epac as a novel effector of airway smooth muscle relaxation

Dysfunctional regulation of airway smooth muscle tone is a feature of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease. Airway smooth muscle contraction is directly associated with changes in the phosphorylation of myosin light chain (MLC), which is increased by R...

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Detalles Bibliográficos
Autores principales: Roscioni, Sara S, Maarsingh, Harm, Elzinga, Carolina RS, Schuur, Janke, Menzen, Mark, Halayko, Andrew J, Meurs, Herman, Schmidt, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823199/
https://www.ncbi.nlm.nih.gov/pubmed/20716113
http://dx.doi.org/10.1111/j.1582-4934.2010.01150.x