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Cyclic AMP increases COX-2 expression via mitogen-activated kinase in human myometrial cells

Cyclic AMP (cAMP) is the archetypal smooth muscle relaxant, mediating the effects of many hormones and drugs. However, recently PGI(2), acting via cAMP/PKA, was found to increase contraction-associated protein expression in myometrial cells and to promote oxytocin-driven myometrial contractility. Cy...

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Detalles Bibliográficos
Autores principales: Chen, Li, Sooranna, Suren R, Lei, Kaiyu, Kandola, Mandeep, Bennett, Phillip R, Liang, Zhiqing, Grammatopoulos, Dimitri, Johnson, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823214/
https://www.ncbi.nlm.nih.gov/pubmed/21854542
http://dx.doi.org/10.1111/j.1582-4934.2011.01413.x