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Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung
Chronic obstructive pulmonary disease (COPD) is characterized by loss of elastic fibres from small airways and alveolar walls, with the decrease in elastin increasing with disease severity. It is unclear why there is a lack of repair of elastic fibres. We have examined fibroblasts cultured from lung...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823220/ https://www.ncbi.nlm.nih.gov/pubmed/22117690 http://dx.doi.org/10.1111/j.1582-4934.2011.01492.x |