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Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung

Chronic obstructive pulmonary disease (COPD) is characterized by loss of elastic fibres from small airways and alveolar walls, with the decrease in elastin increasing with disease severity. It is unclear why there is a lack of repair of elastic fibres. We have examined fibroblasts cultured from lung...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wu, Lian, Qu, Jie-ming, Bai, Chun-xue, Merrilees, Mervyn J, Black, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823220/
https://www.ncbi.nlm.nih.gov/pubmed/22117690
http://dx.doi.org/10.1111/j.1582-4934.2011.01492.x