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Activation of neurokinin-1 receptors up-regulates substance P and neurokinin-1 receptor expression in murine pancreatic acinar cells

Acute pancreatitis (AP) has been associated with an up-regulation of substance P (SP) and neurokinin-1 receptor (NK1R) in the pancreas. Increased SP-NK1R interaction was suggested to be pro-inflammatory during AP. Previously, we showed that caerulein treatment increased SP/NK1R expression in mouse p...

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Detalles Bibliográficos
Autores principales: Koh, Yung-Hua, Moochhala, Shabbir, Bhatia, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823226/
https://www.ncbi.nlm.nih.gov/pubmed/22040127
http://dx.doi.org/10.1111/j.1582-4934.2011.01475.x